Love is losing its meaning and getting harder to do. Will there be love in this day and age that is sad and lonely just for the sake of love itself? Love in Sadness is a love story that captures the mythical fate of love that is so wanted that it doesn't care about limits. In it, love doesn't care what other people think, doesn't mind the pain and anguish it brings, and goes after its destiny. In the drama, Ma Ri is a beautiful girl who married into money and has what seems to be a perfect life. Ironically, her husband, In Wook, who looks like a more than perfect husband, is an obsessive lunatic who is also violently abusive. When he pushes her too far, she asks Jung Won for help. Jung Won is an honest, smart, and handsome plastic surgeon. And when he agrees to help her escape from her husband's control, they fall in love. But In Wook, who is completely obsessed with her, isn't going to let her get away from him. See how hard it is for these two characters to stay together on their hard way to love.