The megalomaniacal supervillain M.O.D.O.K. has long sought his dream of eventually overcoming the globe. However after years of obstacles and failures fighting the Earth's mightiest heroes, M.O.D.O.K. has run his bad company A.I.M. into the ground. Ousted as A.I.M.'s leader, while also managing his falling apart marital relationship as well as family life, the Psychological Microorganism Designed Just for Killing is readied to challenge his best challenge yet: a change of life!